01 Chemistry Research

2021 Topic: Vaccine Development

This event is limited to the first 18 entries

OBJECTIVE & BACKGROUND

Vaccine development has been a critical issue on the minds of many as we work our way through the pandemic.  How are vaccines developed?  How can the timeline be compressed to address an ongoing crisis?  What are the key factors that scientists use to develop vaccines for production and distribution?  How do production, transportation, storage, and distribution impact the efficacy of a vaccine program?

Students will explore these issues by researching events of the past year related to vaccine development, as well as using historical vaccine program information to provide a comprehensive view of where we were, where we are, and where we are going.

EVENT SPECIFIC REQUIREMENTS (updated for clarification on 4/26/2021)

Part 1 - Conduct Literature Research to Address the following 

  • Brief overview of the major classes of vaccine and how each class of vaccines generally works
  • Brief overview of vaccine regulations in the US
  • Challenges associated with COVID-19 vaccine development
  • Challenges associated with assessing the efficacy of the COVID-19 vaccine*
  • How the COVID-19 Pfizer and Moderna vaccines work and how they were rapidly developed*
  • An overview of current challenges (production, distribution, misinformation, federal and local issues) associated with the COVID-19 vaccination efforts

 

Part 2 - Create a Written Report of What You Learned

A research paper that includes information addressing the following and that demonstrates understanding and information from the literature research above.

The introduction should provide the following:

  • Brief overview of the major classes of vaccine and how each class works
  • Brief overview of vaccine regulations in the US

The body of the document should describe the following:

  • Challenges associated with COVID-19 vaccine development
  • Challenges associated with assessing the efficacy of the COVID-19 vaccine*
  • How the COVID-19 Pfizer and Moderna vaccines work and discussion regarding their rapid development*
  • An overview of current challenges (production, distribution, misinformation, federal and local issues) associated with the COVID-19 vaccination efforts

 

The conclusion section should provide an explanation as to why vaccination is an important approach to mitigating the spread of COVID-19.

  • Your written report should approximately 5 pages and may include a few figures
  • Your report must be cited using the ACS style and in-text citation must be included using superscripts. Your journal titles should be abbreviated appropriately
  • At least three of your citations should be primary literature and two must be secondary

  • Use PubMed and other literature search engines to search for relevant articles. If you do not have access to the full article and the paper’s abstracts seem useful, reach out to Dr Keyser, AFTER you confirm with your coach that you cannot access the articles on your own, with the articles’ URLs/DOIs. If possible, she will respond with the respective PDFs (Note: the request may take one or two days to fulfill).  The research must be done by the students!

           * Primary articles must be used to describe the challenges associated with assessing the efficacy of the COVID-19 vaccine, how the COVID-19 Pfizer and Moderna vaccines work and how they were rapidly developed

  • Appendix 1 must consist of your complete list of references used. Your primary and secondary sources should be in a different font color
  • Appendix 2 must have the scans of the first three pages of your primary sources
  • Your cover page must provide a title, authors, school, and team A or B if applicable
  • Your report should be written in Times New Roman, 12 font, and 1.5 spaced
  • Tables, images and figures should be used only when appropriate. If any graphics are taken from other sources, they must be cited using the ACS style

 

Part 3 – Event Day

Presentations will be given over Zoom and should focus on the two topics below: 

  • How the COVID-19 Pfizer and Moderna vaccines work and discussion regarding their rapid development*
  • An overview of current challenges (production, distribution, misinformation, federal and local issues) associated with the COVID-19 vaccination efforts

 

The presentation must be no longer than 3 minutes. Visual representations should be used effectively and must be accompanied by citations if borrowed from any sources. The presentation will be followed by a 3-minute Q&A. All team members should equally contribute to the presentation and the Q&A.

 

Any questions regarding this event can be directed to Sandra Keyser.